ea0070aep673 | Pituitary and Neuroendocrinology | ECE2020
Brooks Emily
, Bachmeier Caroline
, Vorster Juanita
, Sorbello Jane
, Peer Faseeha
, Chikani Viral
, Dimeski Goce
, Ungerer Jacobus
, Pretorius Carel
, Inder Warrick J
Hypertonic saline stimulated copeptin measurements have recently been described for the diagnosis of central DI. A copeptin cut-off of > 4.9 pmol/l has a diagnostic accuracy of 96.5% for distinguishing primary polydipsia from central DI1. A copeptin assay has recently been established in our laboratory. Validation of hypertonic saline-stimulated copeptin concentrations in our local population is needed before this test can be used with confidence in patients pre...